Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504585 | 0.90 | BCHE (0.46) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3504583 | 0.90 | BCHE (0.46) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL22892187 | 0.84 | BCHE (0.49) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL22517725 | 0.82 | BCHE (0.47) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL22101385 | 0.80 | CHRNA7 (0.54) | BCHECHRNA7MEN1KMT2AHTR3E | |
| SCHEMBL21886707 | 0.80 | CHRNA7 (0.54) | BCHECHRNA7MEN1KMT2AHTR3E | |
| SCHEMBL27471274 | 0.80 | SLC18A3 (0.55) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14461205 | 0.80 | CHRNA7 (0.54) | BCHECHRNA7MEN1KMT2AHTR3E | |
| SCHEMBL31083157 | 0.79 | BCHE (0.42) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28262599 | 0.79 | BCHE (0.55) | BCHECHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237416-B1 | POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | disclosed |