Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 11/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14329208 | 0.94 | PIK3CD (0.38) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL15888075 | 0.91 | PIK3CD (0.37) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL14329230 | 0.89 | PIK3CD (0.41) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL14329209 | 0.89 | PIK3CD (0.41) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL14329181 | 0.89 | PIK3CD (0.40) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL14329210 | 0.87 | PIK3CD (0.40) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL4569302 | 0.86 | PIK3CD (0.47) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL14329176 | 0.86 | PIK3CD (0.47) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL14329182 | 0.84 | PIK3CD (0.39) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 | |
| SCHEMBL4569325 | 0.84 | PIK3CD (0.39) | PIK3CDPIK3CGABCB11TBXA2RPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427195-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE LLC (US) | 2019-05-01 | — | — | EP | disclosed |