⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20962975 | 0.76 | — | — | |
| SCHEMBL14307306 | 0.76 | — | — | |
| SCHEMBL14724867 | 0.75 | — | — | |
| SCHEMBL13590080 | 0.75 | — | — | |
| SCHEMBL21037686 | 0.74 | — | — | |
| SCHEMBL25774181 | 0.74 | — | — | |
| SCHEMBL21401736 | 0.72 | — | — | |
| SCHEMBL19771594 | 0.72 | — | — | |
| SCHEMBL24885641 | 0.70 | — | — | |
| SCHEMBL19231441 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |
| WO-2021225912-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | PLIANT THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| US-20190127329-A1 | INHIBITORS FOR THE TREATMENT OF CANCER AND RELATED METHODS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2019-05-02 | — | — | US | disclosed |