⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067714 | 1.00 | — | — | |
| SCHEMBL297152 | 1.00 | — | — | |
| Isopropylamine SCHEMBL1193775 | 0.76 | — | — | |
| SCHEMBL10723942 | 0.72 | — | — | |
| SCHEMBL77706 | 0.72 | — | — | |
| SCHEMBL1064989 | 0.72 | — | — | |
| SCHEMBL2995 | 0.70 | — | — | |
| SCHEMBL652953 | 0.70 | — | — | |
| Isopropylamine SCHEMBL2896130 | 0.70 | — | — | |
| Isopropylamine SCHEMBL10740624 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 763 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507181-B | Propionic acid compound containing 5-substituted tetrahydroisoquinoline, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | claimed |
| CN-117736177-A | Propionic acid compound containing (R) -5-substituted tetrahydroisoquinoline, preparation method and medical application thereof | 中国医学科学院药物研究所 | 2024-03-22 | — | — | CN | claimed |
| WO-2024027844-A1 | PHARMACEUTICAL COMPOSITION AND USE THEREOF | 临港国家实验室 | 2024-02-08 | — | — | WO | claimed |
| CN-117510500-A | Preparation method of asperazepanones alkaloid and application of asperazepanones alkaloid as anti-inflammatory drug | 中国海洋大学 | 2024-02-06 | — | — | CN | claimed |
| CN-117050043-A | 3-phenyl dibenzofuran compound and preparation method and application thereof | 中国海洋大学 | 2023-11-14 | — | — | CN | claimed |
| CN-116726010-A | Application of macrolide derivative in preparation of medicines for inhibiting pro-inflammatory cytokine acting agents | 中国海洋大学 | 2023-09-12 | — | — | CN | claimed |
| US-20230257354-A1 | NOVEL HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2023-08-17 | — | — | US | claimed |
| CN-112654620-B | Novel pyrazolopyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-08-04 | — | — | CN | claimed |
| EP-4211116-A1 | NOVEL HETEROCYCLIC ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2023-07-19 | — | — | EP | claimed |
| US-20230167109-A1 | Aminopiperidine Amides, Derivatives, Compositions, and Uses Related to CXCR4 Modulation | UNIV EMORY (US) | 2023-06-01 | — | — | US | claimed |
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | claimed |
| EP-0217804-A1 | ANALOGS OF SUBSTANCES P. | ENICHEM SPA (IT) | 1987-04-15 | — | — | EP | claimed |
| US-4638046-A | Retro-inverso C-terminal hexapeptide analogues of substance P | ENI-ENTE NAZIONALE IDROCARBURI (IT) | 1987-01-20 | — | — | US | claimed |
| WO-1986003495-A2 | DERIVATIVES OF SUBSTANCES P AND OF FRAGMENTS THEREOF | ENICHEM S.P.A. (IT) | 1986-06-19 | — | — | WO | claimed |
| EP-0161007-A2 | Retro - inverso C-Terminal hexapeptide analogues of substance P | ENI-Ente Nazionale Idrocarburi (IT) | 1985-11-13 | — | — | EP | claimed |
| EP-0082568-B1 | RETRO-INVERSO ANALOGUES OF C-TERMINAL PENTA AND HEXAPEPTIDES OF SUBSTANCE P. | ANIC S.p.A. (IT) | 1984-11-21 | — | — | EP | claimed |
| US-4439360-A | Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P | ANIC S.P.A. (IT) | 1984-03-27 | — | — | US | claimed |
| EP-0082568-A2 | Retro-inverso analogues of C-terminal penta and hexapeptides of substance P. | ANIC S.p.A. (IT) | 1983-06-29 | — | — | EP | claimed |
| US-4315006-A | Benzoxocin derivatives having anxiolytic and anti-convulsant activities | GLAXO GROUP LIMITED (GB) | 1982-02-09 | — | — | US | claimed |
| EP-0024843-A1 | 3,4,5,6-Tetrahydro-2,6-methano-4 beta-amino-1-benzoxocin derivatives, process for their preparation and compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-03-11 | — | — | EP | claimed |