SCHEMBL20968

SCHEMBL20968

O=[C]C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28970113 0.70
SCHEMBL834046 0.70
SCHEMBL29168743 0.70
SCHEMBL1030842 0.70
SCHEMBL3758906 0.70
SCHEMBL8534017 0.67
SCHEMBL1031331 0.67
SCHEMBL27921394 0.63
Carbon Dioxide SCHEMBL6573044 0.63
SCHEMBL28111768 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2516 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024125668-A1 HETEROCYCLIC SUBSTITUTED PENTA-SIX-MEMBERED HETEROARYL DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION AND PREPARATION METHOD THEREFOR 上海海雁医药科技有限公司 2024-06-20 WO claimed
WO-2024114814-A1 JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS ONQUALITY PHARMACEUTICALS CHINA LTD (CN) 2024-06-06 WO claimed
US-20240140986-A1 SYNTHETIC URSOLIC ACID DERIVATIVES AND METHODS OF USE THEREOF REATA PHARMACEUTICALS, INC. 2024-05-02 US claimed
EP-4277916-A1 SYNTHETIC URSOLIC ACID DERIVATIVES AND METHODS OF USE THEREOF Reata Pharmaceuticals, Inc. (US) 2023-11-22 EP claimed
CN-117062800-A Aryl sulfide and preparation method and application thereof 山东康乔生物科技有限公司 2023-11-14 CN claimed
CN-117015548-A Synthetic ursolic acid derivatives and methods of use thereof 里亚塔医药公司 2023-11-07 CN claimed
WO-2022253362-A1 ARYL ISOXAZOLINE COMPOUND AND USE THEREOF 沈阳中化农药化工研发有限公司 2022-12-08 WO claimed
CN-115433177-A Aryl isoxazoline compound and application thereof 沈阳中化农药化工研发有限公司 2022-12-06 CN claimed
WO-2022155614-A1 SYNTHETIC URSOLIC ACID DERIVATIVES AND METHODS OF USE THEREOF REATA PHARMACEUTICALS, INC. (US) 2022-07-21 WO claimed
US-20210300954-A1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2021-09-30 US claimed
WO-1993023384-A1 OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS THE UPJOHN COMPANY (US) 1993-11-25 WO claimed
US-5244863-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-09-14 US claimed
US-5097028-A Herbicides for crops such as wheat, barley, cotton, soybeans BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US claimed
US-5049665-A Cephalosporin derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-09-17 US claimed
EP-0410238-A2 Pyridazinone derivatives BAYER AG (DE) 1991-01-30 EP claimed
US-4943587-A INDOLE COMPOUNDS, TREATMENT OF ARTHRITIS, PAIN OR FEVER WARNER-LAMBERT COMPANY (US) 1990-07-24 US claimed
US-4918070-A Antibiotics BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-04-17 US claimed
EP-0342682-A2 Hydroxamate derivatives of selected nonsteroidal anti-inflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition WARNER-LAMBERT COMPANY (US) 1989-11-23 EP claimed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
US-4160082-A Intermediates for aminoglycoside antibiotics PFIZER INC. (US) 1979-07-03 US claimed