Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670804 | 0.93 | BTK (0.60) | BTK | |
| SCHEMBL16671838 | 0.90 | BTK (0.49) | BTKEGFR | |
| SCHEMBL16670016 | 0.88 | BTK (0.59) | BTK | |
| SCHEMBL16671599 | 0.86 | BTK (0.71) | BTKEGFR | |
| SCHEMBL16670904 | 0.85 | BTK (0.49) | BTK | |
| SCHEMBL16671781 | 0.84 | BTK (0.49) | BTK | |
| SCHEMBL16671783 | 0.84 | BTK (0.49) | BTK | |
| SCHEMBL18045006 | 0.83 | PPARA (0.41) | BTK | |
| SCHEMBL18044915 | 0.83 | BTK (0.55) | BTK | |
| SCHEMBL16671576 | 0.83 | BTK (0.51) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060550-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |