SCHEMBL20975589

SCHEMBL20975589

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)NCCCCC(NC(=O)OC(C)(C)C)C(=O)NC(C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.44
▸ CTSS P25774 3/20 0.42
▸ CTSK P43235 3/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ CAPN1 P07384 1/20 0.39
▸ CXCR3 P49682 1/20 0.39
▸ ITGB3 P05106 1/20 0.39
▸ ITGA2B P08514 1/20 0.39
▸ SIRT5 Q9NXA8 1/20 0.39
▸ TDP1 Q9NUW8 2/20 0.38
▸ MAPT P10636 1/20 0.38
▸ CA1 P00915 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18246147 1.00 GLP1R (0.44) GLP1RCTSSCTSKMEN1GAA
SCHEMBL16909068 0.90 GLP1R (0.48) GLP1RCTSSCTSKMEN1GAA
SCHEMBL16908998 0.90 GLP1R (0.48) GLP1RCTSSCTSKMEN1GAA
SCHEMBL16909223 0.86 GLP1R (0.50) GLP1RCTSSCTSKCAPN1ITGB3
SCHEMBL16909129 0.86 GLP1R (0.50) GLP1RCTSSCTSKCAPN1ITGB3
SCHEMBL18798881 0.86 TDP1 (0.42) GLP1RCTSSCTSKMEN1GAA
SCHEMBL16924988 0.86 TDP1 (0.42) GLP1RCTSSCTSKMEN1GAA
SCHEMBL16921333 0.86 GLP1R (0.39) GLP1RCTSSCTSKMEN1GAA
SCHEMBL16924990 0.84 GLP1R (0.46) GLP1RCTSSCTSKCAPN1CXCR3
SCHEMBL18798879 0.84 GLP1R (0.46) GLP1RCTSSCTSKCAPN1CXCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 — — US disclosed
US-20210171637-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC. 2021-06-10 — — US disclosed
US-20190153107-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC. (US) 2019-05-23 — — US disclosed
US-20190142941-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2019-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171637-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES HRH3, H1-3, CD274 GLP1R 1569/4885CTSS 2649/4885CTSK 2964/4885
US-20190153107-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 GLP1R 304/4885CTSS 796/4885CTSK 894/4885
US-20190142941-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 GLP1R 808/4885CTSS 1222/4885CTSK 1001/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 GLP1R 808/4885CTSS 1222/4885CTSK 1001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback