Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 20/20 | 0.82 |
| ▸ | ESRRB | O95718 | 10/20 | 0.67 |
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | ESRRA | P11474 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842127 | 0.91 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842143 | 0.82 | ESRRG (0.76) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842100 | 0.82 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842018 | 0.80 | ESRRG (1.00) | ESRRGESRRBESR1KCNH2 | |
| SCHEMBL20842014 | 0.80 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL24354483 | 0.77 | ESRRG (0.91) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842220 | 0.77 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2 | |
| SCHEMBL24354524 | 0.77 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2 | |
| SCHEMBL24505376 | 0.77 | ESRRG (0.64) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842168 | 0.77 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480186-B1 | NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT | NOVMETAPHARMA CO LTD (KR) | 2022-06-15 | — | — | EP | disclosed |
| EP-3459936-B1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-04-27 | — | — | EP | disclosed |
| EP-3480186-A1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | Kemimedi Co. Ltd (KR) | 2019-05-08 | — | — | EP | disclosed |