Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 16/20 | 0.63 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 5/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978980 | 0.89 | KDM4C (0.55) | KDM4CKMOKDM2BKDM5AKDM5B | |
| SCHEMBL16034172 | 0.77 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL20978912 | 0.76 | KDM4C (0.61) | KDM4CKMOKDM2BKDM5AKDM5B | |
| SCHEMBL16034424 | 0.74 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL20978836 | 0.74 | KDM4C (0.61) | KDM4CKMOKDM2BKDM5AKDM5B | |
| SCHEMBL16034114 | 0.70 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL20978914 | 0.70 | KDM4C (0.58) | KDM4CKMOKDM2BKDM5AKDM5B | |
| SCHEMBL20978704 | 0.69 | KDM4C (0.55) | KDM4CKMOKDM2BKDM5AKDM5B | |
| SCHEMBL16034731 | 0.68 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033460 | 0.68 | KDM4C (0.81) | KDM4CKDM2BKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |