Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.57 |
| ▸ | KDM5A | P29375 | 6/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.57 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978704 | 0.87 | KDM4C (0.55) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20978714 | 0.83 | KDM4C (0.60) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20978821 | 0.83 | KDM4C (0.61) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20978795 | 0.83 | KDM4C (0.60) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20979007 | 0.81 | KDM4C (0.63) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20978803 | 0.81 | KDM4C (0.58) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20978919 | 0.80 | KDM4C (0.62) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20978982 | 0.80 | KDM4C (0.61) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL20978914 | 0.79 | KDM4C (0.58) | KDM4CKDM5AKDM5BKDM2BJMJD6 | |
| SCHEMBL22442369 | 0.79 | KDM4C (0.67) | KDM4CKDM5AKDM5BKDM2BJMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |