Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.58 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.54 |
| ▸ | KDM5A | P29375 | 7/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16034036 | 0.90 | KDM4C (0.72) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL20978921 | 0.81 | KDM2B (0.62) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16034239 | 0.80 | KDM4C (0.46) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16032942 | 0.73 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16034229 | 0.70 | KDM2B (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033782 | 0.70 | KDM2B (0.78) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16034207 | 0.66 | KDM4C (0.72) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL16033546 | 0.65 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5BKDM4A | |
| SCHEMBL23133740 | 0.65 | CYP19A1 (0.54) | — | |
| SCHEMBL19634864 | 0.65 | KDM4C (0.68) | KDM4CKDM2BKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |