Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.65 |
| ▸ | KDM5A | P29375 | 8/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.51 |
| ▸ | KDM4A | O75164 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033424 | 0.79 | KDM2B (1.00) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20978963 | 0.78 | KDM2B (0.44) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20978856 | 0.78 | KDM4C (0.68) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20978753 | 0.78 | KDM4C (0.52) | KDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL16032737 | 0.77 | KDM2B (0.74) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20978756 | 0.77 | KDM4C (0.54) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20979042 | 0.77 | KDM4C (0.69) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20979069 | 0.76 | KDM4C (0.53) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20978754 | 0.76 | PHF8 (0.58) | KDM2BKDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL20978846 | 0.75 | PHF8 (0.54) | KDM2BKDM5AKDM5BKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |