Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 9/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033745 | 0.76 | KDM5A (0.58) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16126212 | 0.73 | KDM5A (0.43) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16034388 | 0.72 | KDM2B (0.60) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16033691 | 0.72 | KDM5A (0.60) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16034468 | 0.72 | KDM2B (0.43) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16034020 | 0.71 | KDM5A (0.52) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16034584 | 0.71 | KDM5A (0.41) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16033568 | 0.71 | KDM5A (0.62) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16033867 | 0.70 | KDM2B (0.46) | KDM5AKDM5BPHF8KDM4CKDM2B | |
| SCHEMBL16033582 | 0.70 | KDM5A (0.63) | KDM5AKDM5BPHF8KDM4CKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |