Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.61 |
| ▸ | KDM5A | P29375 | 4/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978865 | 0.87 | KDM4C (0.60) | KDM4CKDM5AKDM2BPHF8KDM5B | |
| SCHEMBL20978851 | 0.86 | KDM4C (0.73) | KDM4CKDM5AKDM2BPHF8KDM5B | |
| SCHEMBL20978928 | 0.85 | KDM4C (0.62) | KDM4CKDM5AKDM2BPHF8KDM5B | |
| SCHEMBL20978760 | 0.82 | KDM4C (0.64) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL20978929 | 0.80 | KDM4C (0.56) | KDM4CKDM5AKDM2BKDM5BKDM4A | |
| SCHEMBL16034902 | 0.78 | KDM4C (0.66) | KDM4CKDM5AKDM2BPHF8KDM5B | |
| SCHEMBL16033749 | 0.76 | KDM4C (1.00) | KDM4CKDM5AKDM2BPHF8 | |
| SCHEMBL20978917 | 0.75 | KDM4C (0.67) | KDM4CKDM5AKDM2BPHF8 | |
| SCHEMBL17693323 | 0.74 | KDM4C (0.74) | KDM4CKDM5AKDM2BPHF8 | |
| SCHEMBL20978894 | 0.73 | KDM4C (0.67) | KDM4CKDM5AKDM2BKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |