Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.69 |
| ▸ | KDM5A | P29375 | 9/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 10/20 | 0.49 |
| ▸ | KDM4A | O75164 | 5/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979035 | 0.84 | KDM4C (0.68) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL26208566 | 0.84 | KDM4C (0.69) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL16033624 | 0.82 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL19383330 | 0.81 | KDM4C (0.64) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978869 | 0.77 | KDM4C (0.55) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978963 | 0.75 | KDM2B (0.44) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL16033631 | 0.73 | KDM4C (0.65) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978846 | 0.70 | PHF8 (0.54) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL16034893 | 0.70 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4APHF8 | |
| SCHEMBL20978964 | 0.70 | PHF8 (0.58) | KDM4CKDM5AKDM5BKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |