Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | MITF | O75030 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979246 | 0.93 | HTT (0.72) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL20979224 | 0.93 | HTT (0.86) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL2353462 | 0.93 | HTT (0.86) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL2355507 | 0.92 | HTT (0.73) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL2362757 | 0.92 | MEN1 (0.73) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL2363344 | 0.92 | HTT (0.87) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL20979277 | 0.91 | MEN1 (0.71) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL2363397 | 0.91 | HTT (0.69) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL20979381 | 0.91 | MEN1 (0.73) | HTTL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL2362382 | 0.90 | MEN1 (0.72) | HTTL3MBTL1MEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154966-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | US HEALTH (US) | 2019-05-08 | — | — | EP | disclosed |