Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21730424 | 0.98 | HRH3 (0.41) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL9322304 | 0.97 | CARM1 (0.41) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL21730510 | 0.95 | HRH3 (0.44) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL21730428 | 0.95 | HRH3 (0.44) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL20979250 | 0.95 | USP2 (0.42) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL26941612 | 0.94 | CARM1 (0.41) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL21730448 | 0.94 | HRH3 (0.43) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL21730429 | 0.92 | USP2 (0.44) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL14524678 | 0.92 | CARM1 (0.41) | CARM1PRMT6PRMT8KDM4EUSP2 | |
| SCHEMBL9322214 | 0.91 | HRH3 (0.47) | CARM1PRMT6PRMT8KDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154966-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | US HEALTH (US) | 2019-05-08 | — | — | EP | disclosed |