⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288231 | 1.00 | — | — | |
| SCHEMBL296314 | 1.00 | — | — | |
| SCHEMBL28833351 | 1.00 | — | — | |
| SCHEMBL7703373 | 0.82 | — | — | |
| SCHEMBL22445011 | 0.82 | — | — | |
| SCHEMBL1095348 | 0.82 | — | — | |
| SCHEMBL11050710 | 0.82 | — | — | |
| Water SCHEMBL21496695 | 0.82 | — | — | |
| SCHEMBL3631645 | 0.82 | — | — | |
| Lithium Ion SCHEMBL7705312 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227006-A1 | DIDEUTERATED CAMPTOTHECIN DERIVATIVE AND PREPARATION METHOD THEREFOR | 上海禧耀医药科技有限公司 | 2023-11-30 | — | — | WO | claimed |
| WO-2023226900-A1 | 2-(PIPERAZINE-2-YL) ACETONITRILE DERIVATIVE, PREPARATION METHOD FOR, AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-11-30 | — | — | WO | disclosed |
| WO-2019184866-A1 | PHOSPHATE DERIVATIVES AND USE THEREOF | 朱青 | 2019-10-03 | — | — | WO | disclosed |
| US-8513237-B2 | Sulfonylamino-derivatives as novel inhibitors of histone deacetylase | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-08-20 | — | — | US | disclosed |
| US-20120178741-A1 | Sulfonylamino-Derivatives As Novel Inhibitors Of Histone Deacetylase | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-07-12 | — | — | US | disclosed |
| US-8163733-B2 | Sulfonylamino-derivatives as novel inhibitors of histone deacetylase | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-24 | — | — | US | disclosed |
| US-20100234353-A1 | SULFONYLAMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-16 | — | — | US | disclosed |
| US-7767679-B2 | Sulfonylamino-derivatives as novel inhibitors of histone deacetylase | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-08-03 | — | — | US | disclosed |
| US-20100009988-A1 | PIPERAZINYL-, PIPERIDINYL- AND MORPHOLINYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | EMELEN KRISTOF VAN | 2010-01-14 | — | — | US | disclosed |
| US-7592450-B2 | used to inhibit proliferative conditions, such as cancer and psoriasis, with improved bioavailability and stability | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-22 | — | — | US | disclosed |
| EP-1485354-B1 | SULFONYLAMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA NV (BE) | 2008-05-28 | — | — | EP | disclosed |
| US-20050171347-A1 | Sulfonylamino-derivatives as novel inhibitors of histone deacetylase | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-08-04 | — | — | US | disclosed |
| US-20050165016-A1 | used to inhibit proliferative conditions, such as cancer and psoriasis, with improved bioavailability and stability | JANSSEN PHARMACEUTICA NV (BE) | 2005-07-28 | — | — | US | disclosed |