Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1302209 | 0.84 | TSHR (0.45) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1314449 | 0.84 | TSHR (0.45) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16714013 | 0.83 | TSHR (0.32) | TSHRACHEALDH1A1TDP1 | |
| SCHEMBL1538714 | 0.81 | TSHR (0.47) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1315361 | 0.81 | TSHR (0.47) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2785323 | 0.81 | TSHR (0.47) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8161345 | 0.78 | TSHR (0.50) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL987121 | 0.78 | TSHR (0.50) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1054610 | 0.78 | TSHR (0.50) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1538644 | 0.77 | TSHR (0.43) | TSHRACHENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524992-B2 | Carbon-carbon bond creation method comprising the coupling of a transferable group and an acceptor group | RHODIA CHIMIE (FR) | 2009-04-28 | — | — | US | claimed |
| JP-2007504118-A | — | — | 2007-03-01 | — | — | JP | claimed |
| US-20070010683-A1 | Carbon-carbon bond creation method comprising the coupling of a transferable group and an acceptor group | RHODIA-CHIMIE (FR) | 2007-01-11 | — | — | US | claimed |
| CN-1863751-A | Method for producing a carbon-carbon bond by coupling a transferable group and an acceptor group | RHONE POULENC CHIMIE (FR) | 2006-11-15 | — | — | CN | claimed |
| EP-1658249-A2 | CARBON-CARBON BOND CREATION METHOD COMPRISING THE COUPLING OF A TRANSFERABLE GROUP AND AN ACCEPTOR GROUP | Rhodia Chimie (FR) | 2006-05-24 | — | — | EP | claimed |
| WO-2005023735-A2 | CARBON-CARBON BOND CREATION METHOD COMPRISING THE COUPLING OF A TRANSFERABLE GROUP AND AN ACCEPTOR GROUP | RHODIA CHIMIE (FR) | 2005-03-17 | — | — | WO | claimed |
| US-4839451-A | Processes for the preparation of polysilylenes | XEROX CORPORATION (US) | 1989-06-13 | — | — | US | claimed |
| CN-106633470-A | Weather-resistant automobile ventilating pipe and preparation method thereof | 芜湖瑞德机械科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-101180579-B | Polysilane compound-containing lower layer film forming composition for lithography | NISSAN CHEMICAL IND LTD | 2012-06-27 | — | — | CN | disclosed |
| US-8163460-B2 | Underlayer coating forming composition for lithography containing polysilane compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-7524992-B2 | Carbon-carbon bond creation method comprising the coupling of a transferable group and an acceptor group | RHODIA CHIMIE (FR) | 2009-04-28 | — | — | US | disclosed |
| US-20080318158-A1 | Underlayer Coating Forming Composition for Lithography Containing Polysilane Compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
| CN-101180579-A | Polysilane compound-containing lower layer film forming composition for lithography | NISSAN CHEMICAL IND LTD (JP) | 2008-05-14 | — | — | CN | disclosed |
| CN-1863751-A | Method for producing a carbon-carbon bond by coupling a transferable group and an acceptor group | RHONE POULENC CHIMIE (FR) | 2006-11-15 | — | — | CN | disclosed |
| EP-1658249-A2 | CARBON-CARBON BOND CREATION METHOD COMPRISING THE COUPLING OF A TRANSFERABLE GROUP AND AN ACCEPTOR GROUP | Rhodia Chimie (FR) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005023735-A2 | CARBON-CARBON BOND CREATION METHOD COMPRISING THE COUPLING OF A TRANSFERABLE GROUP AND AN ACCEPTOR GROUP | RHODIA CHIMIE (FR) | 2005-03-17 | — | — | WO | disclosed |
| EP-0291082-B1 | A METHOD FOR THE PRODUCTION OF LIQUID-CRYSTALLINE ORGANOPOLYSILOXANES | TORAY SILICONE COMPANY, LIMITED (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4839451-A | Processes for the preparation of polysilylenes | XEROX CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0291082-A2 | A method for the production of liquid-crystalline organopolysiloxanes | TORAY SILICONE COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | disclosed |
| US-4659852-A | STARTING MATERIAL FOR SILICONE RESINS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010683-A1 | Carbon-carbon bond creation method comprising the coupling of a transferable group and an acceptor group | C9, NUDC, PIK3C2A | TSHR 4834/4885ACHE 3499/4885NPC1 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.