⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682123 | 0.36 | — | — | |
| SCHEMBL3083556 | 0.33 | — | — | |
| SCHEMBL1437284 | 0.33 | — | — | |
| SCHEMBL25230433 | 0.28 | — | — | |
| SCHEMBL12992748 | 0.27 | — | — | |
| SCHEMBL13719381 | 0.24 | — | — | |
| Strontium SCHEMBL30515425 | 0.23 | — | — | |
| Magnesium SCHEMBL31498282 | 0.23 | — | — | |
| SCHEMBL21797 | 0.23 | — | — | |
| Hydrogen Sulfide SCHEMBL1489225 | 0.20 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | PFIZER INC. (US) | 2025-10-16 | — | — | US | disclosed |
| CN-113825758-B | Crystal forms of anti-HBV tetrahydroisoxazolo [4,3-c ] pyridines | 正大天晴药业集团股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| US-11572372-B2 | Anti-HBVtetrahydroisoxazolo[4,3-c]pyridine compounds | MEDSHINE DISCOVERY INC. (CN) | 2023-02-07 | — | — | US | disclosed |
| US-11572372-B2 | Anti-HBVtetrahydroisoxazolo[4,3-c]pyridine compounds | MEDSHINE DISCOVERY INC. (CN) | 2023-02-07 | — | — | US | disclosed |
| CN-111247131-B | anti-HBV (hepatitis B virus) tetrahydroisoxazolo [4,3-c ] pyridine compounds | 正大天晴药业集团股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-111247131-B | anti-HBV (hepatitis B virus) tetrahydroisoxazolo [4,3-c ] pyridine compounds | 正大天晴药业集团股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-20200377517-A1 | ANTI-HBVTETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | MEDSHINE DISCOVERY INC. (CN) | 2020-12-03 | — | — | US | disclosed |
| US-20200377517-A1 | ANTI-HBVTETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | MEDSHINE DISCOVERY INC. (CN) | 2020-12-03 | — | — | US | disclosed |
| WO-2020228745-A1 | CRYSTAL FORM OF TETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUND AGAINST HBV | 正大天晴药业集团股份有限公司 | 2020-11-19 | — | — | WO | disclosed |
| WO-2020228745-A1 | CRYSTAL FORM OF TETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUND AGAINST HBV | 正大天晴药业集团股份有限公司 | 2020-11-19 | — | — | WO | disclosed |
| EP-3712139-A1 | ANTI-HBV TETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
| EP-3712139-A1 | ANTI-HBV TETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
| WO-2019096241-A1 | ANTI-HBV TETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | 正大天晴药业集团股份有限公司 | 2019-05-23 | — | — | WO | disclosed |