SCHEMBL20989702

SCHEMBL20989702

O=C(Oc1ccc(-c2ccc(N3C(=O)C=CC3=O)cc2)cc1)c1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 3/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 2/20 0.56
HTT P42858 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
CACNA1B Q00975 1/20 0.56
APBA1 Q02410 1/20 0.56
DDAH1 O94760 1/20 0.54
KMT2A Q03164 2/20 0.54
MGLL Q99685 11/20 0.51
FAAH O00519 4/20 0.51
PKM P14618 2/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
CCR6 P51684 1/20 0.46
ATM Q13315 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.43
PARP10 Q53GL7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268715 1.00 HSP90AA1 (0.56) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL20938433 1.00 HSP90AA1 (0.56) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL20938446 0.95 HSP90AA1 (0.61) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL12268600 0.95 HSP90AA1 (0.61) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL13477951 0.90 HSP90AA1 (0.48) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL23082310 0.89 HSP90AA1 (0.47) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL21266371 0.88 HSP90AA1 (0.46) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL23082462 0.88 HSP90AA1 (0.46) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL21266459 0.88 HSP90AA1 (0.46) HSP90AA1ALDH1A1HPGDHTTNPSR1
SCHEMBL21266415 0.88 HSP90AA1 (0.46) HSP90AA1ALDH1A1HPGDHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11193066-B2 Polymerizable compound and composition, liquid crystal composite, optical anisotropic body, liquid crystal display device and use thereof JNC CORPORATION (JP) 2021-12-07 US disclosed
US-20190136135-A1 POLYMERIZABLE COMPOUND AND COMPOSITION, LIQUID CRYSTAL COMPOSITE, OPTICAL ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE AND USE THEREOF JNC CORPORATION (JP) 2019-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11193066-B2 Polymerizable compound and composition, liquid crystal composite, optical anisotropic body, liquid crystal display device and use thereof OCIAD2, PYM1, C1S HSP90AA1 3630/4885ALDH1A1 4091/4885HPGD 4527/4885
US-20190136135-A1 POLYMERIZABLE COMPOUND AND COMPOSITION, LIQUID CRYSTAL COMPOSITE, OPTICAL ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE AND USE THEREOF OCIAD2, PYM1, C1S HSP90AA1 3630/4885ALDH1A1 4091/4885HPGD 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.