SCHEMBL2099290

SCHEMBL2099290

CCCCCC(CCCC)OC(=O)C=CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.56
ACHE P22303 1/20 0.45
BACE1 P56817 1/20 0.45
ATM Q13315 1/20 0.41
CTSK P43235 1/20 0.41
GPR84 Q9NQS5 3/20 0.40
FFAR1 O14842 1/20 0.40
TSHR P16473 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102444 1.00 HCAR2 (0.56) HCAR2ACHEBACE1ATMCTSK
SCHEMBL2099288 1.00 HCAR2 (0.56) HCAR2ACHEBACE1ATMCTSK
SCHEMBL2102347 0.98 HCAR2 (0.57) HCAR2ACHEBACE1GPR84FFAR1
Fumaric Acid SCHEMBL10951830 0.98 HCAR2 (0.57) HCAR2ACHEBACE1GPR84FFAR1
SCHEMBL10385864 0.98 HCAR2 (0.57) HCAR2ACHEBACE1GPR84FFAR1
SCHEMBL2101148 0.98 HCAR2 (0.57) HCAR2ACHEBACE1GPR84FFAR1
SCHEMBL10385862 0.98 HCAR2 (0.57) HCAR2ACHEBACE1GPR84FFAR1
SCHEMBL2101146 0.98 HCAR2 (0.57) HCAR2ACHEBACE1GPR84FFAR1
SCHEMBL5611250 0.98 HCAR2 (0.58) HCAR2ACHEBACE1ATMGPR84
SCHEMBL5611251 0.98 HCAR2 (0.58) HCAR2ACHEBACE1ATMGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2598470-B1 FORMULATIONS SYNGENTA LTD (GB) 2021-01-20 EP disclosed
US-9458085-B2 Formulations SYNGENTA LIMITED (GB) 2016-10-04 US disclosed
US-20140249328-A1 FORMULATIONS SYNGENTA LIMITED (GB) 2014-09-04 US disclosed
US-8163458-B2 Method of manufacturing toner, toner, two-component developer, developing device, and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2012-04-24 US disclosed
US-7713675-B2 Method of manufacturing toner SHARP KABUSHIKI KAISHA (JP) 2010-05-11 US disclosed
US-7704664-B2 Method of manufacturing toner and toner SHARP KABUSHIKI KAISHA (JP) 2010-04-27 US disclosed
US-7575843-B2 Method of manufacturing toner and toner SHARP KABUSHIKI KAISHA (JP) 2009-08-18 US disclosed
EP-1262838-B1 RESIN COMPOSITION FOR TONER AND TONER MITSUI CHEMICALS INC (JP) 2009-01-21 EP disclosed
US-20090011351-A1 METHOD OF MANUFACTURING TONER, TONER, TWO-COMPONENT DEVELOPER, DEVELOPING DEVICE, AND IMAGE FORMING APPARATUS SHARP KABUSHIKI KAISHA (JP) 2009-01-08 US disclosed
US-20070202433-A1 Method of manufacturing toner SHARP KABUSHIKI KAISHA (JP) 2007-08-30 US disclosed
US-20070196754-A1 Method of manufacturing toner and toner SHARP KABUSHIKI KAISHA (JP) 2007-08-23 US disclosed
US-20070166638-A1 Method of manufacturing toner and toner SHARP KABUSHIKI KAISHA (JP) 2007-07-19 US disclosed
US-6733941-B1 ETHYLENE POLYMER, PARAFFIN WAX AND BINDER; LOW TEMPERATURE FIXATION, OFFSET RESISTANCE, PRESERVING IMAGE QUALITY MITSUI CHEMICALS, INC. (JP) 2004-05-11 US disclosed
EP-1262838-A1 RESIN COMPOSITION FOR TONER AND TONER Mitsui Chemicals, Inc. (JP) 2002-12-04 EP disclosed
EP-0756208-B1 Resin composition for electrophotographic toner, and toner comprising it MITSUI CHEMICALS INC (JP) 2001-04-11 EP disclosed
US-6011119-A RESIN COMPOSITION SHOWS EXCELLENT CHARGING CHARACTERISTICS WITHOUT A CHARGE CONTROL AGENT; HIGH AND LOW MOLECULAR WEIGHT ADDITION POLYMERS AT LEAST ONE OF WHICH IS FROM AN UNSATURATED ANHYDRIDE AND AN ACRYLOYLOXYALKYL DICARBOXYLIC ACID ESTER MITSUI CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0756208-A1 Resin composition for electrophotographic toner, and toner comprising it MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249328-A1 FORMULATIONS C5, C1S, C1R HCAR2 1504/4885ACHE 2127/4885BACE1 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.