Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | POLG | P54098 | 2/20 | 0.72 |
| ▸ | POLA1 | P09884 | 1/20 | 0.72 |
| ▸ | HPRT1 | P00492 | 9/20 | 0.62 |
| ▸ | PNP | P00491 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15078158 | 1.00 | POLB (0.72) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL15078152 | 0.91 | POLB (0.68) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL15078159 | 0.84 | POLB (0.65) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL19240929 | 0.84 | POLB (0.64) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL30760008 | 0.84 | POLB (1.00) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL17194173 | 0.83 | POLB (0.66) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL15078153 | 0.83 | POLB (0.66) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL15078157 | 0.82 | POLB (0.89) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL15078166 | 0.81 | POLB (0.72) | POLBPOLGPOLA1HPRT1PNP | |
| SCHEMBL15078255 | 0.81 | POLB (0.72) | POLBPOLGPOLA1HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578563-B1 | GUANINE ANALOGS AS TELOMERASE SUBSTRATES AND TELOMERE LENGTH AFFECTORS | GERON CORP (US) | 2021-04-14 | — | — | EP | disclosed |
| EP-2794624-B1 | GUANINE ANALOGS AS TELOMERASE SUBSTRATES AND TELOMERE LENGTH AFFECTORS | GERON CORP (US) | 2019-05-15 | — | — | EP | disclosed |