Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TEC | P42680 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676735 | 1.00 | BTK (0.57) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL18044913 | 0.86 | BTK (0.74) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL16670060 | 0.85 | BTK (0.65) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL21100914 | 0.85 | BTK (0.75) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL20998672 | 0.85 | BTK (0.75) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL20998573 | 0.85 | BTK (0.75) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL16676816 | 0.85 | BTK (0.75) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL16676786 | 0.85 | BTK (0.75) | BTKCYP2C8KCNH2EGFRTEC | |
| SCHEMBL18070180 | 0.84 | BTK (0.42) | BTKCYP2C8KCNH2 | |
| SCHEMBL16676741 | 0.84 | BTK (0.42) | BTKCYP2C8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060550-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |