Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20998499 | 0.93 | BTK (0.42) | BTK | |
| SCHEMBL20998503 | 0.88 | BTK (0.50) | BTK | |
| SCHEMBL18069720 | 0.84 | BTK (0.43) | BTK | |
| SCHEMBL16676743 | 0.84 | BTK (0.43) | BTK | |
| SCHEMBL18044932 | 0.82 | BTK (0.51) | BTK | |
| SCHEMBL18044934 | 0.82 | BTK (0.51) | BTK | |
| SCHEMBL16670714 | 0.82 | BTK (0.57) | BTK | |
| SCHEMBL18070180 | 0.78 | BTK (0.42) | BTK | |
| SCHEMBL16676741 | 0.78 | BTK (0.42) | BTK | |
| SCHEMBL18044938 | 0.76 | BTK (0.54) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060550-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |