Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.61 |
| ▸ | PDCD1 | Q15116 | 17/20 | 0.61 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20999801 | 0.86 | CD274 (0.65) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21451401 | 0.82 | CD274 (0.59) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL20763744 | 0.74 | CD274 (0.66) | CD274PDCD1 | |
| SCHEMBL23949242 | 0.74 | CD274 (0.66) | CD274PDCD1 | |
| SCHEMBL24252544 | 0.73 | PDCD1 (1.00) | CD274PDCD1 | |
| SCHEMBL29392832 | 0.73 | PDCD1 (1.00) | CD274PDCD1 | |
| SCHEMBL25238852 | 0.73 | PDCD1 (1.00) | CD274PDCD1 | |
| SCHEMBL21622980 | 0.72 | CD274 (0.61) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL20969420 | 0.72 | PDCD1 (1.00) | CD274PDCD1 | |
| SCHEMBL29555926 | 0.72 | PDCD1 (1.00) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483142-A1 | AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Guangzhou Maxinovel Pharmaceuticals Co., Ltd. (CN) | 2019-05-15 | — | — | EP | disclosed |