Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 13/20 | 0.64 |
| ▸ | EPAS1 | Q99814 | 14/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21005013 | 0.89 | VEGFA (0.68) | VEGFAEPAS1 | |
| SCHEMBL21005092 | 0.88 | EPAS1 (0.70) | VEGFAEPAS1 | |
| SCHEMBL21005057 | 0.88 | EPAS1 (0.70) | VEGFAEPAS1 | |
| SCHEMBL21004991 | 0.88 | VEGFA (0.67) | VEGFAEPAS1 | |
| SCHEMBL21005015 | 0.85 | EPAS1 (0.72) | VEGFAEPAS1 | |
| SCHEMBL21005008 | 0.83 | VEGFA (0.70) | VEGFAEPAS1 | |
| SCHEMBL21005009 | 0.83 | VEGFA (0.70) | VEGFAEPAS1 | |
| SCHEMBL18688486 | 0.80 | VEGFA (0.72) | VEGFAEPAS1 | |
| SCHEMBL21005439 | 0.79 | EPAS1 (0.69) | VEGFAEPAS1 | |
| SCHEMBL16560893 | 0.79 | VEGFA (1.00) | VEGFAEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3417851-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3417852-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3043784-B9 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-3043784-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-05-15 | — | — | EP | disclosed |