Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17433562 | 0.96 | MDM2 (0.52) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433635 | 0.96 | MDM2 (0.52) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433642 | 0.96 | MDM2 (0.52) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433575 | 0.96 | MDM2 (0.52) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433654 | 0.96 | MDM2 (0.52) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433664 | 0.96 | MDM2 (0.52) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL9779581 | 0.96 | MDM2 (0.52) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433577 | 0.89 | MDM2 (0.45) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433608 | 0.89 | MDM2 (0.45) | MDM2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL17433549 | 0.89 | MDM2 (0.45) | MDM2PGRADRA2AADRA2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356073-B1 | PROCESS FOR THE PREPARATION OF ETHANEDINITRILE | LONZA AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| US-8088351-B2 | Process for the preparation of ethanedinitrile | LONZA LTD. (CH) | 2012-01-03 | — | — | US | disclosed |
| EP-2356073-A1 | PROCESS FOR THE PREPARATION OF ETHANEDINITRILE | Lonza Ltd. (CH) | 2011-08-17 | — | — | EP | disclosed |
| US-20110171102-A1 | PROCESS FOR THE PREPARATION OF ETHANEDINITRILE | LONZA LTD (CH) | 2011-07-14 | — | — | US | disclosed |
| WO-2010052017-A1 | PROCESS FOR THE PREPARATION OF ETHANEDINITRILE | LONZA LTD (CH) | 2010-05-14 | — | — | WO | disclosed |
| EP-2184261-A1 | Process for the preparation of cyanogen from hydrocyanic acid | LONZA LTD. (CH) | 2010-05-12 | — | — | EP | disclosed |