SCHEMBL21007202

SCHEMBL21007202

c1ccc(-n2c3ccccc3c3c4c(c5ccccc5n4-c4ccc5c(c4)C4(c6ccccc6-c6ccccc64)c4ccccc4-5)c4sc5ncccc5c4c32)cc1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR5 O60602 1/20 0.34
PRKCQ Q04759 1/20 0.31
KAT2B Q92831 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21006650 1.00 TLR5 (0.34) TLR5PRKCQKAT2B
SCHEMBL21007600 0.95 TLR5 (0.33) TLR5PRKCQ
SCHEMBL21006723 0.94 TLR5 (0.33) TLR5PRKCQ
SCHEMBL21006727 0.94 TLR5 (0.33) TLR5PRKCQ
SCHEMBL21007252 0.91
SCHEMBL21007245 0.91
SCHEMBL21007619 0.89
SCHEMBL21007596 0.88
SCHEMBL21007681 0.88
SCHEMBL21008150 0.88 MEN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11349081-B2 Azaindolocarbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-05-31 US disclosed
US-20190148646-A1 AZAINDOLOCARBAZOLE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190148646-A1 AZAINDOLOCARBAZOLE COMPOUNDS SLC25A21, OXA1L, OCIAD1 TLR5 2147/4885PRKCQ 4174/4885KAT2B 1488/4885
US-11349081-B2 Azaindolocarbazole compounds SLC25A21, OXA1L, OCIAD1 TLR5 2147/4885PRKCQ 4174/4885KAT2B 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.