Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12758337 | 0.91 | ADORA2A (0.47) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL733124 | 0.91 | ADORA2A (0.47) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL21008084 | 0.91 | ADORA2A (0.47) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL6734193 | 0.91 | ADORA2A (0.47) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL12150032 | 0.91 | ADORA2A (0.47) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL12151845 | 0.91 | ADORA2A (0.47) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL12150844 | 0.91 | ADORA2A (0.47) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL14440914 | 0.88 | PNP (0.45) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL5907189 | 0.86 | PDE4D (0.43) | PDE4DPDE3ASLC29A1PNPADORA2A | |
| SCHEMBL21006002 | 0.85 | PDE4D (0.36) | PDE4DPDE3ASLC29A1PNPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190144484-A1 | ALKYNE CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY | 2019-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144484-A1 | ALKYNE CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | TYMP, PNP, NTPCR | PDE4D 2024/4885PDE3A 1350/4885SLC29A1 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.