SCHEMBL21012436

SCHEMBL21012436

CCOC(=O)COC(=O)OCOC(=O)c1c(F)ccc2c1OB(O)[C@@H]1C[C@H]21

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CAT P04040 1/20 0.56
▸ NLRP3 Q96P20 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23654599 1.00 CAT (0.56) CATNLRP3
SCHEMBL23654578 1.00 CAT (0.56) CATNLRP3
SCHEMBL21012423 0.93 CAT (0.61) CAT
SCHEMBL23655053 0.93 CAT (0.61) CAT
SCHEMBL21012459 0.89 CAT (0.56) CAT
SCHEMBL23654597 0.89 CAT (0.56) CAT
SCHEMBL21012461 0.88 CAT (0.60) CAT
SCHEMBL23655280 0.88 CAT (0.60) CAT
SCHEMBL23655316 0.87 CAT (0.61) CAT
SCHEMBL21012442 0.87 CAT (0.61) CAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999759-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2024-06-04 — — US disclosed
US-20220056055-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA, INC. 2022-02-24 — — US disclosed
US-11180512-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2021-11-23 — — US disclosed
EP-3478693-B1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA INC (US) 2021-07-21 — — EP disclosed
US-20200181177-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF THE MEDICINES COMPANY (SAN DIEGO), LLC 2020-06-11 — — US disclosed
US-10570159-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2020-02-25 — — US disclosed
US-20190233443-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF REMPEX PHARMACEUTICALS, INC. 2019-08-01 — — US disclosed
US-10294249-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2019-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220056055-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BTD, BLK, BCL6B CAT 106/4885NLRP3 384/4885
US-10294249-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885NLRP3 384/4885
US-20200181177-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BTD, BLK, BCL6B CAT 106/4885NLRP3 384/4885
US-10570159-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885NLRP3 384/4885
US-11180512-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885NLRP3 384/4885
US-11999759-B2 Boronic acid derivatives and therapeutic uses thereof BTD, BLK, BCL6B CAT 106/4885NLRP3 384/4885
US-20190233443-A1 BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF BTD, BLK, BCL6B CAT 106/4885NLRP3 384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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