Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | FCER2 | P06734 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129317 | 0.85 | CYP1A2 (0.63) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL26129197 | 0.85 | CYP1A2 (0.63) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL26129199 | 0.85 | CYP1A2 (0.63) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL20834910 | 0.85 | TSHR (0.53) | MMP8ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL16964256 | 0.85 | CYP1A2 (0.53) | MMP8KMT2ATSHREGFRMME | |
| SCHEMBL8309569 | 0.85 | TSHR (0.53) | MMP8ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL29313120 | 0.83 | GAA (0.62) | ALDH1A1KMT2AEPHX2TSHRL3MBTL1 | |
| SCHEMBL30562908 | 0.82 | HPGD (0.63) | ALDH1A1SMN1; SMN2KMT2ATSHRL3MBTL1 | |
| SCHEMBL30567894 | 0.82 | HPGD (0.63) | ALDH1A1SMN1; SMN2KMT2ATSHRL3MBTL1 | |
| SCHEMBL8411454 | 0.82 | KMT2A (0.54) | MMP8ALDH1A1KMT2ATSHREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294269-B2 | Dipeptidyl ketoamide compounds and their use for the treatment and/or prevention of fat accumulation | LANDSTEINER GENMED, S.L. (ES) | 2019-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294269-B2 | Dipeptidyl ketoamide compounds and their use for the treatment and/or prevention of fat accumulation | DPP4, DPP3, DPP8 | MMP8 1029/4885ALDH1A1 1198/4885SMN1; SMN2 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.