Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAT | P04040 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 14/20 | 0.36 |
| ▸ | HTR2A | P28223 | 11/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21012534 | 0.82 | CAT (0.67) | CAT | |
| SCHEMBL21012590 | 0.82 | CAT (0.67) | CAT | |
| SCHEMBL21012609 | 0.82 | CAT (0.67) | CAT | |
| SCHEMBL21012589 | 0.79 | CAT (0.69) | CAT | |
| Xeruborbactam SCHEMBL23655292 | 0.78 | CAT (1.00) | CAT | |
| Xeruborbactam SCHEMBL22854594 | 0.78 | CAT (1.00) | CAT | |
| Xeruborbactam SCHEMBL21012432 | 0.78 | CAT (1.00) | CAT | |
| Xeruborbactam SCHEMBL21012430 | 0.78 | CAT (1.00) | CAT | |
| Xeruborbactam SCHEMBL21012607 | 0.78 | CAT (1.00) | CAT | |
| SCHEMBL24995934 | 0.77 | CAT (0.60) | CAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180512-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| EP-3478693-B1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA INC (US) | 2021-07-21 | — | — | EP | disclosed |
| US-20200181177-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | THE MEDICINES COMPANY (SAN DIEGO), LLC | 2020-06-11 | — | — | US | disclosed |
| US-10570159-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20190233443-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. | 2019-08-01 | — | — | US | disclosed |
| US-10294249-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2019-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294249-B2 | Boronic acid derivatives and therapeutic uses thereof | BTD, BLK, BCL6B | CAT 106/4885HTR2C 4865/4885HTR2A 4563/4885 |
| US-20200181177-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | BTD, BLK, BCL6B | CAT 106/4885HTR2C 4865/4885HTR2A 4563/4885 |
| US-10570159-B2 | Boronic acid derivatives and therapeutic uses thereof | BTD, BLK, BCL6B | CAT 106/4885HTR2C 4865/4885HTR2A 4563/4885 |
| US-11180512-B2 | Boronic acid derivatives and therapeutic uses thereof | BTD, BLK, BCL6B | CAT 106/4885HTR2C 4865/4885HTR2A 4563/4885 |
| US-20190233443-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | BTD, BLK, BCL6B | CAT 106/4885HTR2C 4865/4885HTR2A 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.