⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896312 | 0.76 | — | — | |
| SCHEMBL9063449 | 0.76 | TP53 (0.47) | — | |
| SCHEMBL28823468 | 0.75 | — | — | |
| SCHEMBL744169 | 0.73 | — | — | |
| SCHEMBL5525436 | 0.71 | — | — | |
| SCHEMBL13725798 | 0.71 | — | — | |
| SCHEMBL1417959 | 0.71 | — | — | |
| SCHEMBL9494396 | 0.71 | — | — | |
| SCHEMBL14040005 | 0.71 | — | — | |
| SCHEMBL185750 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 659 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11738087-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2023-08-29 | — | — | US | claimed |
| CN-107580596-B | Sulfimidoylpurine ketone compounds and derivatives for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-07-14 | — | — | CN | claimed |
| US-20200109144-A1 | Sulfonimidoylpurinone Compounds | HOFFMANN-LA ROCHE INC. (US) | 2020-04-09 | — | — | US | claimed |
| EP-3294740-A1 | NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | H. Hoffnabb-La Roche Ag (CH) | 2018-03-21 | — | — | EP | claimed |
| CN-107580596-A | For treating and preventing the new sulphur imido acyl group purinone compound and derivative of virus infection | 豪夫迈·罗氏有限公司 | 2018-01-12 | — | — | CN | claimed |
| US-20170275286-A1 | Novel Sulfonimidoylpurinone Compounds and Derivatives for the Treatment and Prophylaxis of Virus Infection | HOFFMANN-LA ROCHE INC. (US) | 2017-09-28 | — | — | US | claimed |
| WO-2016180695-A1 | NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2016-11-17 | — | — | WO | claimed |
| US-20160326177-A1 | Novel Sulfonimidoylpurinone Compounds and Derivatives for the Treatment and Prophylaxis of Virus Infection | HOFFMANN-LA ROCHE INC. (US) | 2016-11-10 | — | — | US | claimed |
| CN-102947300-B | Alkaloid amino ester derivative and pharmaceutical composition thereof | 奇斯药制品公司 | 2016-09-21 | — | — | CN | claimed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | claimed |
| EP-0346108-A2 | Anti-infective nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-12-13 | — | — | EP | claimed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | claimed |
| US-4659734-A | BACTERICIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1987-04-21 | — | — | US | claimed |
| US-4619943-A | NEUROLEPTIC AGENTS | RAO KOPPAKA V | 1986-10-28 | — | — | US | claimed |
| EP-0158513-A2 | Antiviral compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-10-16 | — | — | EP | claimed |
| US-4419522-A | ANTITUMOR AGENTS | CHINOIN GYOGYSZER VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-12-06 | — | — | US | claimed |
| EP-0040435-B1 | PEPTIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Eisai Co., Ltd. (JP) | 1983-07-20 | — | — | EP | claimed |
| EP-0040435-A1 | Peptide derivatives and process for the preparation thereof | Eisai Co., Ltd. (JP) | 1981-11-25 | — | — | EP | claimed |
| US-4002665-A | Process for substituted cyclohexenes and its products | WARNER-LAMBERT COMPANY (US) | 1977-01-11 | — | — | US | claimed |