Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021436 | 0.84 | HTT (0.37) | HTTLMNAHPGDMEN1KMT2A | |
| SCHEMBL21020557 | 0.83 | NPC1 (0.32) | HTTLMNAHPGDMEN1KMT2A | |
| SCHEMBL21019722 | 0.83 | MEN1 (0.32) | MEN1KMT2AALDH1A1RECQL | |
| SCHEMBL21022006 | 0.82 | MEN1 (0.39) | HTTLMNAHPGDMEN1KMT2A | |
| SCHEMBL21022107 | 0.81 | MEN1 (0.35) | HTTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL21019976 | 0.81 | HTT (0.37) | HTTLMNAHPGDMEN1KMT2A | |
| SCHEMBL21021274 | 0.81 | HTT (0.36) | HTTLMNAHPGDMEN1KMT2A | |
| SCHEMBL18146465 | 0.80 | MEN1 (0.51) | HTTLMNAHPGDMEN1KMT2A | |
| SCHEMBL18146469 | 0.80 | MEN1 (0.51) | HTTLMNAHPGDMEN1KMT2A | |
| SCHEMBL18146466 | 0.80 | MEN1 (0.51) | HTTLMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |