Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.73 |
| ▸ | F2 | P00734 | 2/20 | 0.73 |
| ▸ | F10 | P00742 | 2/20 | 0.73 |
| ▸ | PLAT | P00750 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.70 |
| ▸ | RELA | Q04206 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.66 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.66 |
| ▸ | PNLIP | P16233 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363184 | 0.93 | PLAU (0.69) | PLAUF2F10PLATNPC1 | |
| SCHEMBL19040075 | 0.90 | PLAU (0.66) | PLAUF2F10PLATNPC1 | |
| SCHEMBL24460276 | 0.90 | P2RX1 (0.77) | PLAUF2F10PLATNPC1 | |
| SCHEMBL6285639 | 0.90 | TMPRSS4 (0.67) | PLAUF2F10PLATNPC1 | |
| SCHEMBL14363179 | 0.90 | PLAU (0.65) | PLAUF2F10PLATNPC1 | |
| SCHEMBL30844207 | 0.89 | PLAU (0.72) | PLAUF2F10PLATNPC1 | |
| SCHEMBL14363291 | 0.89 | PLAU (0.72) | PLAUF2F10PLATNPC1 | |
| SCHEMBL14363181 | 0.88 | NPC1 (0.66) | PLAUF2F10PLATNPC1 | |
| SCHEMBL13812666 | 0.87 | P2RX1 (0.82) | NPC1RAB9ALMNATP53NFKB1 | |
| SCHEMBL17774840 | 0.87 | NPC1 (0.62) | PLAUF2F10PLATNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109148-A1 | SMALL MOLECULE INHIBITORS OF SARS-COV-2 INFECTIONS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |