Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450596 | 0.85 | TSHR (0.45) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL12677361 | 0.85 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL594507 | 0.85 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL15827369 | 0.84 | TSHR (0.41) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL12390916 | 0.81 | TSHR (0.41) | TSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21023737 | 0.81 | TSHR (0.41) | TSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL311323 | 0.81 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1537333 | 0.81 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL16115060 | 0.81 | — | — | |
| SCHEMBL16039188 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493291-B1 | PEHAM DENDRIMERS FOR USE IN AGRICULTURE | DENDRITIC NANOTECHNOLOGIES INC (US) | 2019-05-22 | — | — | EP | disclosed |