Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.75 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21025245 | 0.92 | SYK (0.78) | SYK | |
| SCHEMBL21025480 | 0.86 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL10196088 | 0.86 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL21024993 | 0.85 | SYK (0.78) | SYKFLT3AURKB | |
| SCHEMBL21024989 | 0.80 | SYK (0.76) | SYKFLT3AURKB | |
| SCHEMBL21025246 | 0.80 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL10196069 | 0.80 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL524686 | 0.78 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL524685 | 0.78 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL29996480 | 0.78 | SYK (1.00) | SYKFLT3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119772-B1 | HETEROARYL SIK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-05-22 | — | — | EP | disclosed |