Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.67 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.67 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344010 | 0.87 | MAPT (0.73) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL15695725 | 0.85 | MAPT (0.70) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL19932691 | 0.84 | MAPT (0.69) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL30520940 | 0.83 | MAPT (0.73) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL15369106 | 0.83 | MAPT (0.71) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL22157909 | 0.83 | MAPT (0.69) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL29200203 | 0.82 | MAPT (0.61) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL23888071 | 0.81 | MAPT (1.00) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL6575386 | 0.81 | MAPT (1.00) | MAPTTDP1ALDH1A1THRBLMNA | |
| SCHEMBL11853848 | 0.81 | MAPT (1.00) | MAPTTDP1ALDH1A1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190160025-A1 | AGENTS USEFUL FOR TREATING OBESITY, DIABETES AND RELATED DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-30 | — | — | US | disclosed |