Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TSPO | P30536 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027003 | 0.91 | GLA (0.74) | GLAKDM4ETSPOAPEX1P2RX4 | |
| SCHEMBL15732891 | 0.86 | GLA (0.87) | GLAKDM4EAPEX1P2RX4PTGDR2 | |
| Cridanimod SCHEMBL3372087 | 0.86 | GLA (1.00) | GLAKDM4EAPEX1P2RX4ALDH1A1 | |
| Cridanimod SCHEMBL29373385 | 0.86 | GLA (1.00) | GLAKDM4EAPEX1P2RX4ALDH1A1 | |
| Cridanimod SCHEMBL3801665 | 0.86 | GLA (1.00) | GLAKDM4EAPEX1P2RX4ALDH1A1 | |
| Cridanimod SCHEMBL3375823 | 0.85 | GLA (0.96) | GLAKDM4EAPEX1P2RX4ALDH1A1 | |
| Cridanimod SCHEMBL27895128 | 0.85 | GLA (0.96) | GLAKDM4EAPEX1P2RX4ALDH1A1 | |
| Cridanimod SCHEMBL3375819 | 0.85 | GLA (0.96) | GLAKDM4EAPEX1P2RX4ALDH1A1 | |
| SCHEMBL21027247 | 0.84 | GLA (0.51) | GLAKDM4EPTGDR2MARK4HTT | |
| SCHEMBL27547403 | 0.84 | KDM4E (0.72) | GLAKDM4ETSPOAPEX1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | Stingthera, Inc. | 2021-01-07 | — | — | US | disclosed |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | SILICON SWAT, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | SILICON SWAT, INC. | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | GLA 364/4885KDM4E 4553/4885TSPO 3555/4885 |
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | GLA 364/4885KDM4E 4553/4885TSPO 3555/4885 |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | STING1, IRF3, CGAS | GLA 364/4885KDM4E 4553/4885TSPO 3555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.