Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21028032 | 0.86 | PTGDR2 (0.52) | PTGDR2TBXA2RPTGDRSLC6A3 | |
| SCHEMBL21028332 | 0.82 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL21027877 | 0.81 | PTGDR2 (0.45) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL21028008 | 0.80 | PTGDR2 (0.45) | PTGDR2TBXA2RPTGDRSLC6A3 | |
| SCHEMBL21027863 | 0.78 | PTGDR2 (0.52) | PTGDR2TBXA2RPTGDRSLC6A3 | |
| SCHEMBL21027842 | 0.77 | PTGDR2 (0.46) | PTGDR2TBXA2RPTGDRSLC6A3 | |
| SCHEMBL21027847 | 0.77 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRSLC6A3 | |
| SCHEMBL21027862 | 0.76 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDRSLC6A3 | |
| SCHEMBL21027977 | 0.75 | PTGDR2 (0.51) | PTGDR2TBXA2RPTGDRSLC6A3 | |
| SCHEMBL21027843 | 0.75 | PTGDR2 (0.51) | PTGDR2TBXA2RPTGDRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |