Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24141359 | 0.81 | HTR2A (0.42) | HTR2AHTR2CSIGMAR1KDM4ERECQL | |
| SCHEMBL24141362 | 0.77 | HTR2A (0.46) | HTR2AHTR2CSIGMAR1KDM4ERECQL | |
| SCHEMBL21028328 | 0.72 | KCNH2 (0.35) | PTGDR2 | |
| SCHEMBL21028013 | 0.71 | PTGDR2 (0.40) | PTGDR2 | |
| SCHEMBL21027841 | 0.71 | PTGDR2 (0.36) | PTGDR2 | |
| SCHEMBL21027980 | 0.70 | PTGDR2 (0.39) | PTGDR2 | |
| SCHEMBL24141358 | 0.70 | KDM4E (0.37) | HTR2AHTR2CSIGMAR1KDM4EALDH1A1 | |
| SCHEMBL21028284 | 0.69 | HTR2A (0.46) | HTR2AHTR2CSIGMAR1PTGDR2 | |
| SCHEMBL11842462 | 0.67 | P2RX4 (0.46) | KDM4EPTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL1104626 | 0.66 | HTR2A (0.66) | HTR2AHTR2CSIGMAR1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |