⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27708376 | 0.79 | — | — | |
| SCHEMBL28740426 | 0.76 | USP2 (0.30) | — | |
| SCHEMBL29265197 | 0.75 | CYP1A2 (0.38) | — | |
| SCHEMBL24612830 | 0.74 | — | — | |
| SCHEMBL2456465 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL3466316 | 0.72 | CA1 (0.36) | — | |
| SCHEMBL777745 | 0.69 | NPSR1 (0.33) | — | |
| SCHEMBL777322 | 0.67 | NPSR1 (0.32) | — | |
| SCHEMBL11203255 | 0.67 | — | — | |
| SCHEMBL20610342 | 0.66 | USP2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430590-A | Cyclopropyl compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-108026101-B | Fused pyrimidine compound or salt thereof | 大鹏药品工业株式会社 | 2020-06-26 | — | — | CN | disclosed |
| US-20140051626-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2014-02-20 | — | — | US | disclosed |
| US-20120130104-A1 | CYCLOPROPENES-GENERATING DEVICES TO CONTROL RIPENING PROCESSES OF AGRICULTURAL PRODUCTS | YOO SANG-KU (KR) | 2012-05-24 | — | — | US | disclosed |
| US-8163244-B2 | For controlled ripening of plants to improve storage stability of agricultural products; Device includes container for cyclopropene precursor e.g. 1-methyl-1-(methanesulfonyloxy)-2-(trimethylsilyl)cyclopropane, another area for reaction of said precursors into e.g. methylcyclopropene, and a sprayer | YOO SANG-KU (KR) | 2012-04-24 | — | — | US | disclosed |
| US-20080286426-A1 | Cyclopropenes-Generating Devices to Control Ripenning Processes of Agricultural Products | YOO SANG-KU | 2008-11-20 | — | — | US | disclosed |
| EP-1947955-A1 | CYCLOPROPENES-GENERATING DEVICES TO CONTROL RIPENING PROCESSES OF AGRICULTURAL PRODUCTS | Yoo, Sang-Ku (KR) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007058473-A1 | CYCLOPROPENES-GENERATING DEVICES TO CONTROL RIPENING PROCESSES OF AGRICULTURAL PRODUCTS | YOO SANG-KU (KR) | 2007-05-24 | — | — | WO | disclosed |