Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15812927 | 0.89 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL15812924 | 0.89 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL355538 | 0.89 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL13161373 | 0.86 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3CBSMN1; SMN2PIK3CA | |
| SCHEMBL20061285 | 0.85 | PIK3CG (0.57) | PIK3CDPIK3CGPIK3CBCYP1A2CYP2C9 | |
| SCHEMBL20061283 | 0.85 | PIK3CD (0.63) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL15813050 | 0.85 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL16583284 | 0.83 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL356484 | 0.83 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL10163694 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3046563-B1 | SUBSTITUTED AMINOPYRIMIDINE COMPOUNDS AS PI3-KINASE INHIBITORS | CALITOR SCIENCES LLC (US) | 2019-05-29 | — | — | EP | disclosed |