Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 17/20 | 0.64 |
| ▸ | SLC5A2 | P31639 | 12/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029901 | 0.90 | SLC5A1 (0.54) | SLC5A1SLC5A2AR | |
| SCHEMBL21028847 | 0.88 | SLC5A1 (0.66) | SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL24029616 | 0.88 | SLC5A1 (0.53) | SLC5A1SLC5A2AR | |
| SCHEMBL24029612 | 0.81 | SLC5A1 (0.47) | SLC5A1SLC5A2AR | |
| SCHEMBL24038262 | 0.80 | SLC5A1 (0.47) | SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL24030004 | 0.80 | SLC5A1 (0.47) | SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL15748717 | 0.79 | SLC5A1 (1.00) | SLC5A1SLC5A2 | |
| SCHEMBL22972815 | 0.79 | SLC5A1 (0.66) | SLC5A1SLC5A2 | |
| SCHEMBL24030116 | 0.79 | SLC5A1 (0.47) | SLC5A1SLC5A2 | |
| SCHEMBL20787214 | 0.78 | SLC5A1 (0.77) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489226-B1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | LEXICON PHARMACEUTICALS INC (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3489226-A1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | Lexicon Pharmaceuticals, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |