Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038678 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL27979614 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMEN1PKM | |
| SCHEMBL16560783 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1KMT2AMEN1PKM | |
| SCHEMBL16281259 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1KMT2AMEN1PKM | |
| SCHEMBL14090887 | 0.71 | KDM4E (0.39) | KDM4ESLC18A3ALDH1A1KMT2AMEN1 | |
| SCHEMBL18027472 | 0.71 | KDM4E (0.39) | KDM4ESLC18A3ALDH1A1KMT2AMEN1 | |
| SCHEMBL6051905 | 0.70 | KDM4E (0.33) | KDM4ESLC18A3TDP1OPRL1 | |
| SCHEMBL14115127 | 0.70 | KMT2A (0.41) | KDM4EALDH1A1KMT2AMEN1PKM | |
| SCHEMBL3961125 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1PKM | |
| SCHEMBL4279010 | 0.68 | SLC18A3 (0.35) | SLC18A3KMT2AMEN1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10300171-B2 | Resorbable crosslinked form stable membrane | GEISTLICH PHARMA AG (CH) | 2019-05-28 | — | — | US | disclosed |