Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631051 | 1.00 | GABRR1 (0.31) | GABRR1PLGPLATLMNA | |
| SCHEMBL13631050 | 0.83 | GABRR1 (0.31) | GABRR1PLGPLATLMNA | |
| SCHEMBL13806339 | 0.82 | GABRR1 (0.33) | GABRR1PLGPLATLMNA | |
| SCHEMBL4109097 | 0.82 | GABRR1 (0.50) | GABRR1PLGPLATLMNA | |
| SCHEMBL4428766 | 0.82 | GABRR1 (0.50) | GABRR1PLGPLATLMNA | |
| SCHEMBL4428770 | 0.82 | GABRR1 (0.50) | GABRR1PLGPLATLMNA | |
| SCHEMBL24690908 | 0.79 | NAMPT (0.32) | — | |
| SCHEMBL24690910 | 0.79 | NAMPT (0.32) | — | |
| SCHEMBL24690909 | 0.79 | NAMPT (0.32) | — | |
| SCHEMBL24690457 | 0.79 | NAMPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301322-B2 | Processes for the preparation of edoxaban and intermediates thereof | APOTEX INC. (CA) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301322-B2 | Processes for the preparation of edoxaban and intermediates thereof | VKORC1, CYP2C9, VKORC1L1 | GABRR1 1607/4885PLG 63/4885PLAT 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.