Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.47 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.44 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.44 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.44 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19629401 | 1.00 | MTOR (0.53) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL21394004 | 1.00 | MTOR (0.53) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL20692837 | 1.00 | MTOR (0.53) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL10124249 | 0.97 | MTOR (0.50) | MTORPIK3CAPIK3R1 | |
| SCHEMBL14811270 | 0.97 | MTOR (0.50) | MTORPIK3CAPIK3R1 | |
| SCHEMBL14811271 | 0.97 | MTOR (0.50) | MTORPIK3CAPIK3R1 | |
| SCHEMBL23505802 | 0.92 | MTOR (0.52) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL21375707 | 0.92 | MTOR (0.52) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL21029901 | 0.92 | MTOR (0.56) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL21375479 | 0.92 | MTOR (0.52) | MTORPIK3CAPIK3R1RICTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019101853-A1 | TREATMENT OF SKIN DISORDERS | PIQUR THERAPEUTICS AG (CH) | 2019-05-31 | — | — | WO | disclosed |