Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 9/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19823828 | 0.84 | AOC3 (0.74) | AOC3SLC6A2SLC6A4SLC6A3GRIN1 | |
| SCHEMBL17664808 | 0.76 | CA1 (0.43) | AOC3CYP2D6 | |
| SCHEMBL17112356 | 0.74 | AOC3 (0.59) | AOC3SLC6A2SLC6A4SLC6A3MMP1 | |
| SCHEMBL16334290 | 0.72 | AOC3 (0.62) | AOC3SLC6A2SLC6A4SLC6A3MMP1 | |
| SCHEMBL4199855 | 0.72 | AOC3 (0.62) | AOC3SLC6A2SLC6A4SLC6A3MMP1 | |
| SCHEMBL12454628 | 0.72 | AOC3 (0.62) | AOC3SLC6A2SLC6A4SLC6A3MMP1 | |
| SCHEMBL15241688 | 0.71 | AOC3 (0.56) | AOC3SLC6A2SLC6A4MMP1CYP2D6 | |
| SCHEMBL3684962 | 0.69 | AOC3 (0.54) | AOC3SLC6A2SLC6A4SLC6A3MMP1 | |
| SCHEMBL5367825 | 0.69 | AOC3 (0.54) | AOC3SLC6A2SLC6A4MMP1CYP2D6 | |
| SCHEMBL27796486 | 0.69 | AOC3 (0.50) | AOC3SLC6A4MMP1CYP2D6MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052556-A1 | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | LUPIN LTD (IN) | 2021-02-25 | — | — | US | disclosed |
| US-20190275012-A9 | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | LUPIN LIMITED (IN) | 2019-09-12 | — | — | US | disclosed |
| US-20190160045-A1 | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | LUPIN LTD (IN) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052556-A1 | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | MALT1, PTP4A1, PTPRO | AOC3 2046/4885SLC6A2 4416/4885SLC6A4 3914/4885 |
| US-20190275012-A9 | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | MALT1, PTP4A1, PTPRO | AOC3 2046/4885SLC6A2 4416/4885SLC6A4 3914/4885 |
| US-20190160045-A1 | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | MALT1, PTP4A1, PTPRO | AOC3 2046/4885SLC6A2 4416/4885SLC6A4 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.