Sugi Predict

Sugi Predict / Compounds / SCHEMBL21031239

SCHEMBL21031239

SCHEMBL21031239

Cc1cc(-c2ccc(-c3ccccc3)cc2)cc(-c2cccc(-c3ccccc3)c2)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ CYP19A1 P11511 1/20 0.44
▸ KDM4E B2RXH2 3/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ HPGD P15428 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ ADORA3 P0DMS8 1/20 0.41
▸ ADORA2B P29275 1/20 0.41
▸ ADORA1 P30542 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ GRM5 P41594 1/20 0.41
▸ ESR1 P03372 1/20 0.41
▸ ESR2 Q92731 1/20 0.41
▸ CRHR1 P34998 1/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21031238 0.98 MEN1 (0.49) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL19986167 0.98 MEN1 (0.49) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL21031241 0.96 MEN1 (0.56) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL21031240 0.94 MEN1 (0.53) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL13203397 0.93 MEN1 (0.51) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL30928310 0.90 MEN1 (0.61) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL18538850 0.90 MEN1 (0.61) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL16373472 0.90 MEN1 (0.61) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL16376443 0.90 MEN1 (0.61) MEN1KMT2ACYP19A1KDM4EL3MBTL1
SCHEMBL18325404 0.89 MEN1 (0.51) MEN1KMT2AKDM4EL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 — — US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 — — US disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 MEN1 3802/4885KMT2A 1221/4885CYP19A1 2824/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 MEN1 3802/4885KMT2A 1221/4885CYP19A1 2824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.